PROFESSIONAL EXPERIENCE
Principal Scientist
1999 to Feb. 2005--Abbott Laboratories, Diagnostics Division
Core R&D Analytical Chemistry—Supervised a group of bioanalytical Ph.D scientists. Responsible for macromolecular analysis (proteins, peptides, glycoconjugates, polymers) and bioanalytical methods development. .
Senior Research Biochemist
1997- 1998—Abbott Laboratories, Diagnostics Division
ADD Analytical Research--Protein characterization and methods development for proteins in immunoassays. Analysis by mass spectrometry, capillary electrophoresis, HPLC, and other protein bioanalytical techniques.
Senior Research Analytical Chemist
1995-1996--Abbott Pharmaceutical Products Division
Analytical Research and Development—Analytical methods development for Recombinant Pro-Urokinase and other recombinant proteases and protein drug candidates. All work done in a cGMP environment.
Senior Research Biochemist
1989-1994--Abbott Diagnostics Division
Lead Biochemist—1989-1993. Antigen identification, purification, and characterization for Abbott Chagas Antibody EIA 510(k) submission. Product launched 7/95.
Developed Chagas Radioimmunoprecipitation assay for seroconfirmation.
Developed Chagas confirmatory EIA for R & D use.
Lead Scientist— 1994. Recombinant antigen identification, purification, and characterization for CBER-approvable Chagas’ disease blood screens.
Lead Biochemist-1995. Maldi-TOF mass spectrometry and capillary electrophoresis methods for recombinant protein characterization.
Staff Scientist
1987-1989 --Biotherapeutics, Inc.
Co-director of ATAC project to produce, purify, and test monoclonal antibody heteroconjugates as candidates for human cancer immunotherapy. IND for phase I clinicals accepted by FDA.
Research Associate
1981-1987 --St. Jude Children’s Research Hospital, Biochemistry Dept.
Structure-function studies of calmodulin-dependent enzymes.
Localization of interaction sites of calmodulin for calmodulin-dependent enzymes.
Postdoctoral Fellow of the American Cancer Society
Rockefeller University, Dept. of Developmental and Molecular Biology, 1979-1981
Purified and microsequenced H-2 histocompatability antigens. Identified, purified, and characterized cell adhesion molecules involved in embryonic development.
